Posts Categorized: Life Sciences Letters

Hybrid Simulation of Heterogeneous Cell Populations

By Steffen Waldherr, Philip Trennt, and Mubashir Hussain
Published October 4, 2016.

The modeling of heterogeneous dynamic cell populations based on population balance equations is an important tool to describe the interaction between intracellular dynamics and population dynamics. However, the numerical simulation of such models remains challenging for …

Testing the Pattern of AKT Activation by Variational Parameter Estimation

By Daniel Kaschek, Frauke Henjes, Max Hasmann, Ulrike Korf, and Jens Timmer
Published November 10, 2016.

Dynamic modeling has become one of the pillars of understanding complex biological systems from a mechanistic point of view. In particular, ordinary differential equations are frequently used to model the dynamics …

A Novel Digital Phantom Using an Optical Noncontact Measurement System

By Xiaodong Yang (Member, IEEE), Aifeng Ren, Tianqiao Zhu, and Fangming Hu
Published May 13, 2016.

Digital phantoms are vital for various biomedical researches. Traditional phantoms include theoretical models and voxel models reconstructed from medical images. It has been demonstrated that the homogeneous phantom filled with uniform …

libSBOLj 2.0: A Java Library to Support SBOL 2.0

By Zhen Zhang, Tramy Nguyen, Nicholas Roehner, Göksel Misirli, Matthew Pocock, Ernst Oberortner, Meher Samineni, Zach Zundel, Jacob Beal, Kevin Clancy, Anil Wipat, and Chris J. Myers
Published March 24, 2016.

The Synthetic Biology Open Language (SBOL) is an emerging data standard for representing synthetic biology designs. …

Exact Moment Dynamics for Feedforward Nonlinear Chemical Reaction Networks

By Eduardo D. Sontag (Fellow, IEEE) and Abhyudai Singh (Member, IEEE) Published September 29, 2015.
We introduce a class of chemical reaction networks for which all moments can be computed by finite-dimensional linear differential equations. This class allows second and higher order reactions, subject to certain …

Displacement of Bacterial Plasmids by Engineered Unilateral Incompatibility

By Robert Gooding-Townsend, Steven Ten Holder, and Brian Ingalls
Published August 19, 2015.

Bacterial plasmids employ copy number control systems to ensure that they do not overburden their hosts. Plasmid incompatibility is caused by shared components of copy number control systems, resulting in mutual inhibition of replication. …

About the Life Sciences Letters

IEEE Life Sciences Letters (LSL) is a new digital, peer reviewed open access journal. The LSL publication will focus on shorter papers with a quick turnaround, in the area of personalized medicine, pharmaceutical engineering, synthetic biology, and systems biology. Learn more about the scope here. Information for authors can be found here.


Paolo BonatoInterim Editor-in-Chief
Paolo Bonato

Senior Editors

Leroy HoodSenior Editor for Personalized Medicine
Leroy Hood

Richard D. BraatzSenior Editor for Pharmaceutical Engineering
Richard D. Braatz

Ron WeissSenior Editor for Synthetic Biology
Ron Weiss

Hiroaki KitanoSenior Editor for Systems Biology
Hiroaki Kitano

For biographies and the list of all of the editors, click here.