By Xiaodong Yang (Member, IEEE), Aifeng Ren, Tianqiao Zhu, and Fangming Hu
Published May 13, 2016.
Digital phantoms are vital for various biomedical researches. Traditional phantoms include theoretical models and voxel models reconstructed from medical images. It has been demonstrated that the homogeneous phantom filled with uniform tissue is accurate enough for wearable antenna design, body-centric channel modeling, etc. Therefore, it is interesting and necessary to investigate the novel approach of generating digital phantoms using an optical noncontact measurement system. In this letter, the point cloud data are first obtained; then, they are simplified via principal component analysis; finally, by applying surface reconstruction and mesh simplification techniques, a digital Chinese phantom is established. To verify the usability of the phantom, numerical calculation is performed to check E-fields at different positions on the body. Results sufficiently prove the feasibility of the train of thought presented in this letter.
By Zhen Zhang, Tramy Nguyen, Nicholas Roehner, Göksel Misirli, Matthew Pocock, Ernst Oberortner, Meher Samineni, Zach Zundel, Jacob Beal, Kevin Clancy, Anil Wipat, and Chris J. Myers
Published March 24, 2016.
The Synthetic Biology Open Language (SBOL) is an emerging data standard for representing synthetic biology designs. The goal of SBOL is to improve the reproducibility of these designs and their electronic exchange between researchers and/or genetic design automation tools. The latest version of the standard, SBOL 2.0, enables the annotation of a large variety of biological components (e.g., DNA, RNA, proteins, complexes, small molecules, etc.) and their interactions. SBOL 2.0 also allows researchers to organize components into hierarchical modules, to specify their intended functions, and to link modules to models that describe their behavior mathematically. To support the use of SBOL 2.0, we have developed the libSBOLj 2.0 Java library, which provides an easy to use Application Programming Interface (API) for developers, including manipulation of SBOL constructs, serialization to and from an RDF/XML file format, and migration support in the form of conversion from the prior SBOL 1.1 standard to SBOL 2.0. This letter describes the libSBOLj 2.0 library and key engineering decisions involved in its design.
IEEE Life Sciences Letters (LSL) is a new digital, peer reviewed open access journal. The LSL publication will focus on shorter papers with a quick turnaround, in the area of personalized medicine, pharmaceutical engineering, synthetic biology, and systems biology. Learn more about the scope here. Information for authors can be found here.
Life Sciences Letters
Senior Editor for Personalized Medicine
Senior Editor for Pharmaceutical Engineering
Richard D. Braatz
Senior Editor for Synthetic Biology
Senior Editor for Systems Biology
For biographies and the list of all of the editors, click here.