Posts Categorized: Vol: 1 Issue 1

By Jing Su and Michael A. Henson, Senior Member, IEEE
Published July 13, 2015.

A critical decision in the mammalian cell cycle is whether to pass through the restriction point and enter the cell cycle. In this study, we modeled the decision making system of mammalian cell …

By Robert Gooding-Townsend, Steven Ten Holder, and Brian Ingalls
Published August 19, 2015.

Bacterial plasmids employ copy number control systems to ensure that they do not overburden their hosts. Plasmid incompatibility is caused by shared components of copy number control systems, resulting in mutual inhibition of replication. …

By Burook Misganaw, Student Member, IEEE and M. Vidyasagar, Life Fellow, IEEE
Published June 30, 2015.

In multi-class machine learning problems, one needs to distinguish between nominal labels which do not have any natural ordering, and ordinal labels which are ordered. Ordinal labels are pervasive in biology, …

By Ana S. Rufino Ferreira, Justin Hsia, and Murat Arcak Published June 16, 2015.

We propose a lateral inhibition system and analyze contrasting patterns of gene expression. The system consists of a set of compartments interconnected by channels. Each compartment contains a …

By John H. Abel, Lukas A. Widmer, Peter C. St. John, Jörg Stelling, and Francis J. Doyle III Published June 4, 2015.

In the mammalian suprachiasmatic nucleus (SCN), a population of noisy cell-autonomous oscillators synchronizes to generate robust circadian rhythms at the …